Metronidazole is an anti-inflammatory drug of the nitroimidazole class, which is usually particularly effective for anaerobic infections. Although metronidazole is less likely than cephalosporins and β-lactams to cause a disulfiram-like lethal chemical reaction with alcohol, drinking alcohol after taking metronidazole can significantly reduce pharmacokinetics and pharmacokinetics, seriously affecting the drug effect of metronidazole. In addition, drinking alcohol after taking metronidazole may significantly increase the chance of allergic reactions and may cause definite clinical adverse reactions, such as severe nausea, vomiting, acid reflux, heartburn, regurgitation, etc. In more serious cases, allergic symptoms such as itching of the skin and red rash around the body may occur.