In general, the interval between plasma donations cannot be shorter than 15 days, and plasma can be donated up to two times in a month. The process of plasma donation is to separate the patient’s blood, then transfuse the blood cells back into the patient, and the remaining part is plasma. After separating the plasma, it is then available for clinical application, through which the plasma can be processed into various blood products, such as frozen plasma, fresh plasma, cold precipitation, human albumin, etc. After plasma donation, the body loses a certain amount of plasma. The main component of plasma is water, which also includes some albumin, globulin, inorganic ions and various clotting factors, etc. The recovery time for plasma components varies, with water recovered within 24 hours, but albumin and some clotting factors take longer, usually around 10 days. In order to ensure the health of the donor, the interval between plasma donations should not be less than 15 days.