Pain in the anterior side of the armpit is considered to be related to overwork, lymphadenitis, and breast hyperplasia. 1. Overexertion: If the patient has been doing strenuous physical labor or strenuous exercise in recent times, it may lead to damage to the soft tissues around the armpit and cause pain. 2. Lymphadenitis: Lymphadenitis can be triggered when the skin and mucous membrane around the armpit or armpit are infected by germs, and the lymph nodes in the affected area may be enlarged, and the local area may be red, swollen and painful. 3. Breast Hyperplasia: The pain in the front side of the armpit in female patients may be caused by the fluctuation of estrogen level in the body. When estrogen levels are high, the breast glands will proliferate, manifesting as breast swelling or nipple pain. Changes in estrogen levels can occur around the time of the menstrual cycle or as a result of dramatic mood swings. If the pain in the anterior side of the armpit is serious, the patient should go to the hospital in time for the appropriate examination, such as blood routine, X-ray examination, etc., to clarify the cause of the disease, and follow the doctor’s instructions for symptomatic treatment.