Crooked mouth after facial nerve injury generally refers to facial paralysis, which is mostly caused by infection, trauma, tumor, etc. Drug treatment, surgical treatment, rehabilitation treatment, etc. can be carried out according to doctor’s instructions. 1. Drug treatment: if in the acute stage of idiopathic facial nerve palsy, glucocorticoids such as prednisone and dexamethasone can be used as prescribed; antiviral drugs such as acyclovir and valacyclovir can be used as prescribed; antibiotics such as amoxicillin capsule and doxycycline tablets can be used for infected cases as prescribed by the doctor; vitamin B12 can be used as prescribed by the doctor for nutrition of nerves. 2. Surgical treatment: if conservative treatment is not obvious, you can follow the doctor’s instructions for surgical treatment, common surgical treatment methods are facial nerve decompression surgery. 3. Rehabilitation therapy: iodine iontophoresis, acupuncture or electroacupuncture can be used during the recovery period. Specific treatment methods need to go to the hospital to confirm the diagnosis, under the guidance of the doctor to choose. If the patient’s mouth is seriously distorted, he/she can change his/her diet, such as sucking liquids through a straw. Patients are advised to go to the hospital for regular review, and the doctor can adjust the treatment plan according to the review.