There is no such thing as the most effective and fastest way to get rid of dandruff. Generally use medication, dietary adjustments and other methods. It is necessary to clarify the causes of dandruff, such as fungal infection, seborrheic dermatitis, psoriasis and so on. 1. Fungal infection: antifungal treatment first. For example, topical terbinafine hydrochloride, miconazole nitrate. You can wash your hair with ketoconazole lotion. You can also take oral antifungal drugs such as terbinafine and itraconazole. 2. Seborrheic dermatitis: you can use topical calcium-modulated phosphatase inhibitors such as tacrolimus ointment, hormone creams such as hydrocortisone butyrate, use selenium disulfide shampoo to wash your hair, and take oral vitamin B2, vitamin B6 and other drugs. At the same time, pay attention to regular cleaning of the scalp, avoiding the intake of greasy. Spicy stimulating food, avoid staying up late. 3. Psoriasis: at this time, you can use topical vitamin D3 derivatives such as carbotriol, calcium-modulated phosphatase inhibitors such as pimecrolimus ointment, coal tar, etc., and you can take oral medications such as Avitamin A and methotrexate. There may be other reasons for dandruff, it is recommended to go to the hospital in a timely manner, a clear diagnosis, symptomatic treatment, drugs need to be used in accordance with medical advice.