The instructions for the rabies vaccine contain some instructions on usage and some contraindications. For pre-exposure prophylaxis, there are certain contraindications. If the rabies vaccine is given during an acute illness, if there is a significant fever, or if the rabies vaccine is given during pregnancy, the vaccine should be given after this state; however, for post-exposure prophylaxis, since rabies is a lethal disease, there are no such contraindications. If the rabies vaccine is used in China, only intramuscular injection is available, so it can only be given intramuscularly in the deltoid area of the upper arm, not intravascularly or by other means such as subcutaneous injection. Injections should not be given intramuscularly in the gluteus maximus muscle, as this may affect the immunization effect. The instructions for the rabies vaccine sometimes indicate that strenuous exercise, strong tea and coffee, and alcohol are prohibited. These are relative contraindications that generally do not affect the effectiveness of the rabies vaccine particularly significantly, but it is best to pay attention to them when you can.