Toothache usually does not lead to low platelets, toothache is usually a clinical symptom of endodontitis, apical periodontitis and other diseases, low platelets are usually seen in aplastic anemia, thrombocytopenic purpura and other diseases, as follows. 1. Toothache: pulpitis usually leads to spontaneous pain in the affected teeth, hot and cold stimulation pain, apical periodontitis usually leads to tooth percussion pain, occlusal pain. In addition, dental trauma in the oral cavity, osteomyelitis of the jawbone, dentin sensitivity can also lead to toothache. 2. Low platelets: it may be aplastic anemia, myelodysplastic syndromes caused by reduced platelet formation, or thrombocytopenic purpura leading to excessive platelet destruction. Toothache and low platelet may have other reasons, if the above symptoms, it is recommended to go to the hospital in time, with the help of doctors to clarify the cause of the disease after targeted treatment.