The presence of increased blood sedimentation in rheumatoid arthritis should be considered a case of exacerbation of the disease or an active phase of the disease, which requires active treatment with medications. Non-steroidal drugs are also called the first-line treatment drugs for rheumatoid arthritis. First, you should choose to use non-steroidal anti-inflammatory drugs to relieve the pain caused by arthritis. Secondly, anti-rheumatic immunosuppressants should be selected to relieve the condition, such as methotrexate, leflunomide, hydroxychloroquine sulfate, and rheumatism, etc. Depending on the severity of the patient’s condition and whether there are complications and internal organ involvement, 2-3 immunosuppressants can be selected for treatment as appropriate. If the current patient has severe pain and significant joint swelling, the NSAIDs can also be replaced with hormonal drugs to quickly relieve the patient’s inflammation. In addition, if the patient has serious visceral damage, or if the condition allows, you can also choose to use biological agents for treatment, the vast majority of patients through active treatment, the condition can be controlled or remission, the remission of the condition will be followed by a decrease in blood sedimentation index.