Whether the pathology report of esophageal squamous epithelial hyperplasia is serious or not will depend on whether cancer is present. Esophageal squamous epithelial hyperplasia is usually caused by prolonged inflammation and proliferative changes. If the pathology report shows that esophageal squamous epithelial hyperplasia is inflammatory hyperplasia, it means the risk of cancer is low, therefore, if esophageal squamous epithelial hyperplasia is not very serious, you can use medicines such as Mosapride Citrate Tablets and Ranitidine Hydrochloride Capsules under the guidance of doctor to relieve the symptom and have a regular recheck. If the pathology report shows that the esophageal squamous epithelial hyperplasia is moderate hyperplasia or severe hyperplasia, it means that the risk of cancer is high and relatively serious, and such patients need to be closely followed up, and the esophageal mucosa should be peeled off or resected according to the specific situation. If the pathology report shows esophageal squamous epithelial hyperplasia, it is necessary to communicate with the doctor in time and standardize the treatment under the doctor’s guidance.