Clinical manifestations of gastric cancer Symptoms of gastric cancer in various stages 1. More than 70% of early gastric cancer have no obvious symptoms, and with the development of the disease, non-specific symptoms similar to gastritis or gastric ulcer may gradually appear, including epigastric fullness and discomfort or hidden pain, acidity, belching, nausea, occasional vomiting, loss of appetite, indigestion, positive fecal occult blood or black stool, unexplained weakness, emaciation or progressive anemia, etc. Yu Yingjian, Department of General Surgery, Shijiazhuang First Hospital 2. Symptoms of progressive gastric cancer (i.e. middle to late stage gastric cancer) are seen as pain in the stomach area, often biting, not obviously related to eating, or similar to peptic ulcer pain, which can be relieved after eating. There is a feeling of fullness and heaviness in the upper abdomen, anorexia, abdominal pain, nausea, vomiting, diarrhea, emaciation, anemia, edema, fever, etc. Cardia cancer mainly manifests as discomfort and pain under the saber, pain or pain behind the sternum, accompanied by obstruction to eating or difficulty in swallowing; cancer of the fundus and subcardia often has no obvious symptoms until the tumor is huge and necrotic ulceration causes bleeding in the upper gastrointestinal tract, or when the tumor infiltration extends to the pancreatic orifice causing difficulty in swallowing; cancer of the body of the stomach is more common in the distended type, with pain and discomfort appearing later; cancer of the less curved side of the gastric sinus is most common in the ulcerated type. When the tumor extends to the pylorus, it can cause nausea, vomiting and other symptoms of pylorus obstruction. When the cancer spreads, it can cause ascites, hepatomegaly, jaundice and metastasis of lung, brain, heart, prostate, ovary, bone marrow, etc. and the corresponding symptoms appear.