Girls’ perineum long meat bumps can be considered related to warts, vestibular gland cysts or vulvar tumors, etc. After clarifying their nature, they can be treated by surgery, physical therapy or medication. 1. Condyloma acuminatum: mainly to remove the warts locally, can be removed by physical therapy, such as freezing, laser, electrocautery, etc. Huge warts can be surgically removed; topical 5% imiquimod cream or 5% fluorouracil cream can also be used to remove warts; warts smaller, urethral warts, topical medication to remove warts, or after physical therapy, can be prevented from recurring by photodynamic therapy. 2. Vestibular cysts: to ensure local cleanliness during the attack, the cysts can be observed when asymptomatic, for larger cysts or recurrent attacks, cystostomy can be carried out; when the acute inflammation attack, you can choose quinolone, metronidazole or cephalosporin and other joint anti-infective. 3. Vulvar tumor: If there is benign vulvar tumor (such as fibroma), it is usually treated by local excision along the tumor; if there is vulvar squamous intraepithelial lesion, low-grade lesion with symptoms can be treated with imiquimod cream or fluorouracil cream, etc., and there are extensive foci of which can be treated with laser therapy, and high-grade lesions need to be treated with excision. There may be other reasons for women’s perineal pimples, so it is recommended to go to a regular hospital to clarify the nature of the lesion and then follow the doctor’s instructions for symptomatic treatment, and pay attention to regular follow-up.