Folic acid supplementation is required during all pregnancies. Folic acid prevents malformations in fetal development and is also beneficial to the body. Folic acid can be taken in the morning or at bedtime, and is not subject to time constraints; it can be taken at any time. The absorption of the drug will not be affected by the time, but it should be noted that it should be taken after meals to avoid irritation to the stomach and intestines. Folic acid should be taken until the third trimester of pregnancy, each person’s constitution is different, must be taken in accordance with the dosage ordered by the doctor, can not be increased privately. Many foods also contain folic acid, such as green vegetables can also be supplemented with folic acid through food. In order to provide sufficient nutrition for the fetus during pregnancy, we must pay attention to diet, eat more protein-rich foods, prohibit picky eating, and must achieve balanced nutrition. At the same time, we should pay attention to the obstetric examination, so as to avoid malformation of the fetus in the process of development.