What is the cause of glutamyl transpeptidase 200+. Transpeptidase is mainly distributed inside the kidney cells, followed by the pancreas and liver more often. Patients with acute hepatitis or active hepatitis, cirrhosis can cause moderate elevation, especially in primary liver cancer, the level of transpeptidase is very hyperactive and can cause significant elevation of transpeptidase, which can reach more than ten times of normal. The reference value of transpeptidase is generally <40. If it exceeds the range, it can be considered as high, physiologically elevated. For example, overworked men, chronic alcoholism can also cause it, and taking some drugs, such as anti-epileptic drugs, can also cause an increase of transpeptidase in the blood. Patients with liver damage, such as long-term alcohol consumption, viral hepatitis infection, and people with a heavy liver burden, can also cause an increase in transpeptidase. If glutamyl transpeptidase is elevated, it should pay attention to the problem of liver disease, especially in patients with liver cancer, and patients with viral hepatitis, which can also be significantly elevated. The transpeptidase should be examined in time to clarify the cause of the disease, and if the problem is found, it should be treated in time.