What happened to the blisters on top of the mosquito bites?

Mosquito bites on the top of the bag blisters (i.e., blisters) to consider the possibility of suffering from insect bite dermatitis, is due to the mosquito bite toxin secretion in the local caused by direct irritation, but also toxins so that the local skin to produce an allergic reaction.
Mosquito bites, mosquito secretion of toxins may contain acidic substances, these substances can directly make the local cell dehydration, protein denaturation, etc., damage to the local skin and thus cause blisters.
The toxins secreted by mosquito bites can also cause allergic reactions, i.e., mast cells are activated to release inflammatory active chemical factors such as pentazocine, histamine, arachidonic acid, etc., leading to local microvascular dilatation, increase in vascular permeability, and increased osmotic pressure, which results in the appearance of windburns, blisters, and other symptoms on the skin.
It is recommended that patients with blisters on top of the bag after being bitten by mosquitoes go to the hospital in a timely manner, follow the doctor’s instructions for treatment, avoid squeezing and scratching, and avoid secondary infections.