Acquired coagulation dysfunction is the opposite of congenital coagulation dysfunction, that is, acquired factors that lead to coagulation dysfunction, due to which patients with coagulation dysfunction develop a range of symptoms of bleeding. Common disorders of acquired coagulation dysfunction include: i. Vitamin K deficiency, where various causes lead to insufficient vitamin K concentration and decreased density of coagulation factors associated with vitamin K, resulting in coagulation dysfunction. It often causes endogenous coagulation pathway as well as exogenous coagulation pathway dysfunction, and the patient develops a series of symptoms of poisoning, commonly including acquired coagulation dysfunction caused by rat poisoning. Second, there are other diseases caused by diffuse intravascular coagulation, such as serious infections, pathological obstetrics, severe trauma, etc., can cause secondary diffuse intravascular coagulation due to various reasons resulting in reduced coagulation factor function deficiency, and eventually also appear acquired coagulation dysfunction.