The reasons for high uric acid on febuxostat include poor dietary control, drug resistance, and random stopping of the drug, which need to be used in strict compliance with the doctor’s instructions. 1. Poor dietary control: If you have a bad diet or eat high purine food during the period of taking the drug, it will also cause the rise of uric acid. It is recommended to eat a light diet, quit smoking and drinking, drink more water, avoid seafood and animal offal, get enough rest and avoid staying up late. 2. Resistance: If the patient has a resistance to febuxostat, the drug can not play a normal pharmacological effect, can not reduce uric acid and thus manifested in uric acid is also high, you can change the drug under the guidance of the doctor to control uric acid. 3. Arbitrary discontinuation: febuxostat belongs to the long-term drug, if the patient arbitrarily stop the drug will cause the rebound of uric acid, so you need to strictly comply with the doctor’s instructions for the use of drugs, can not be unauthorized discontinuation of the drug to reduce the drug. It is recommended that patients go to the hospital in a timely manner to find out the cause and follow the doctor’s instructions, so as not to delay the condition.