Patients with IgA nephropathy are generally able to do general anesthesia surgery. IgA nephropathy is a chronic glomerulonephritis caused by the abnormal deposition of immunoglobulin A in the glomerular tunica albuginea area, which pathologically manifests as tunica albuginea hyperplasia and deposition of immune complexes in the tunica albuginea area with IgA as the main component. Clinically, the main manifestations are hematuria, proteinuria, edema, hypertension, and certain severe patients can be combined with impaired renal function. If the creatinine of IgA patients is in the normal range and the glomerular filtration rate is generally normal, it is possible to consider receiving general anesthesia. However, if creatinine is elevated and glomerular filtration rate is reduced, when receiving general anesthesia, it is necessary to consider that renal function may be adversely affected, and medications with less renal impairment can be selected, while the dosage of medication is adjusted according to creatinine clearance. In addition, anesthesia carries certain risks, especially general anesthesia, so patients need to actively consult with a specialist before surgery.