“Postherpetic neuralgia” is one of the most intractable diseases in the medical field, and has the notorious name of “undead cancer”. At present, the pain department adopts comprehensive treatment methods and has achieved more satisfactory treatment results. 1.Local treatment Lidocaine cream or capsaicin can be applied locally. 2, drug treatment such as neurotoxin, the drug is the use of cowpox vaccination rabbit skin tissue purification exquisite liquid, with the nervous system and the immune system of cell function repair effect, and has an analgesic effect. It can also be used in combination with analgesics such as chimantin and antidepressants such as amitriptyline. 3.Pain therapy instrument treatment With the development of pain science, under the guidance of pain theory, many special instruments have been developed for the treatment of pain, such as transcutaneous electrical stimulation, laser, ultra-laser pain therapy instruments, etc. These instruments have become one of the effective means of treatment of the disease. 4.Nerve block and nerve destruction treatment According to the pain site selectively block the nerves that conduct pain, such as paravertebral nerves and sympathetic nerves, can slow down the number and frequency of abnormal impulses issued by the nerves, so that the nerves get enough nutrition and rest, a considerable number of patients can be cured. For some refractory patients, the pain-conducting nerves can be selectively destroyed to achieve long-term pain relief. 5, the current international advanced pain relief technology Spinal cord electrical stimulation, central target-controlled analgesic infusion system (programmable computer morphine pump), etc., the most advanced international pain relief technology, the technology can effectively control the intractable neuralgia after herpes zoster, and the effect is better. In conclusion, one should neither be afraid nor take it lightly when one has shingles. Active treatment in the early stages of the disease will not only promote early healing of the herpes and reduce pain, but will also have a positive impact on the prevention of post-herpetic neuralgia.