Soreness of the muscles at the back of the thighs may be caused by strain of the muscle groups at the back of the thighs, and the symptoms can be relieved through general treatment, physical therapy, medication and other methods. 1. General treatment: soreness of the posterior thigh muscles should pay attention to bed rest, so that the posterior thigh muscles get enough rest, which is conducive to relieving the symptoms. At the same time, avoid walking, running and other sports, so as not to aggravate the symptoms of pain. 2. Physiotherapy: within 48 hours of the soreness of the posterior thigh muscles, ice packs can be used to apply cold compresses to the painful parts, which is conducive to eliminating swelling and relieving the symptoms of soreness. 72 hours later, hot towels or hot water bags can be used to apply hot compresses to the painful parts, which is conducive to promoting blood circulation and improving the symptoms. 3. Medication: Oral non-steroidal anti-inflammatory drugs, such as ibuprofen, celecoxib, meloxicam, etc., to reduce the symptoms of muscle soreness in the back of the thigh. At the same time, you can also orally take Cao Wu Methylin tablets, etc., which can relieve swelling and accelerate the reduction of symptoms. It is recommended to use medication under the guidance of a doctor, not blindly self-medication to avoid adverse effects.