Angiokeratoderma does not usually heal on its own, and angiokeratoderma requires prompt treatment. Angiokeratoderma belongs to the skin tumor, due to the blood vessels are dilated after some stimulation, resulting in hyperkeratosis of the skin, manifested as single or multiple raised slightly soft compressible red to purplish-red papules, affecting the external image. If left untreated, it can have a huge impact on the patient’s mental health. The disease can also involve other systems, resulting in a variety of complications. For small angiokeratomas with no specific symptoms, treatment can be left untreated for the time being, focusing on a balanced diet, more exercise, and maintaining a good routine. For angiokeratoderma that is large in size and already affects the appearance, it can be treated by surgery, laser cosmetic technology and other ways. It is recommended that after diagnosis of angiokeratoderma, patients should go to regular hospitals in time and follow the advice of dermatologists for standardized diagnosis and treatment.