Yellow patches on the skin at the corner of the eyes may be caused by diseases such as blepharospasm, blepharophimosis, and eyelid xanthoma. 1. Blepharospasmosis: the etiology of blepharospasmosis is not yet clear, and it is mostly considered to be related to ultraviolet rays in sunlight. Patients will have benign conjunctival plaques, mainly yellow in color, and patients with blepharospasm will also have inflammatory symptoms such as conjunctival congestion and itchy eyes. 2. Blepharoplasty: Blepharoplasty is mainly caused by lipid-containing tissue cells in the skin, and the main symptom of patients is the appearance of yellowish, soft, flat, wart-like elevations on the eyelid skin. 3. Eyelid yellow tumor: the pathogenesis of eyelid yellow tumor is not clear, considering that the patient’s blood lipid increase and other factors. The patient will have symptoms such as orange-yellow bean-sized papules at the inner canthus of the eyelid, and yellow tumors may also appear on the lower eyelids and palms of the hands of the patients. Patients with symptoms of yellow plaques on the eyelids should go to the hospital in time to find out the specific cause of the disease and take treatment measures under the guidance of the doctor.