The itchy and yellowish water from the pierced ear may be caused by local bacterial infection, which can be improved by local disinfection, application of antibacterial ointment and oral antibacterial medication. 1. Local disinfection: you can use hydrogen peroxide solution to rinse the ear hole, clean the pus, you can use a cotton swab dipped in iodophor disinfectant to disinfect the treatment. 2. Apply antibacterial ointment: you can apply erythromycin ointment and mupirocin cream for anti-infection treatment. 3. Oral antimicrobial drugs: For patients with more serious infections, they need to take cephalosporin antibiotics, macrolide antibiotics for treatment, such as cefixime, roxithromycin and so on. These drugs can cause gastrointestinal irritation, allergy and other adverse reactions, and need to be used under the guidance of a doctor.