The effects of immunotherapy for tumor treatment are both good and bad. The effect of immunotherapy on patients in clinic varies significantly due to the different methods adopted and the different physical conditions of patients. At present, immunotherapy methods commonly used in clinical treatment of tumors include immune checkpoint inhibitors, immunomodulators, tumor vaccines, and overdose immunocytotherapy. In recent years, immune checkpoint inhibitors have achieved good efficacy in advanced non-small cell lung cancer, malignant melanoma and other solid tumors, but not all tumors can benefit from the treatment. Immunomodulators have been used clinically for many years, but their efficacy has never been satisfactory. A variety of tumor vaccines have been developed, but the overall therapeutic effect has not been satisfactory. Although over-immunocytotherapy has achieved better results in some patients, it is generally ineffective in patients with few tumor-specific antigens in their bodies. Moreover, some patients will experience lethal side effects after treatment due to the immune storm.