Pain in the ankle needs to be treated depending on the cause. Treatment mainly includes rest + physiotherapy, medication and surgery. 1. Rest + physical therapy: most of the pain in the foot and neck is caused by fatigue injury. First of all, we need to rest and let the body recover naturally, secondly, patients can put ice compresses on the feet after the pain occurs, and after 72 hours, we can put local hot compresses, auxiliary massages, massage, microwave and other physical treatments to relieve the pain. 2. Medication: Patients who do not see pain relief or patients whose pain is caused by gout can choose oral medication for treatment. Patients with fatigue injury can choose non-steroidal anti-inflammatory drugs such as ibuprofen, diclofenac sodium, etc. Gout patients can choose colchicine, benzbromarone, etc. 3. Surgical treatment: If patients have trauma, they need to be alert to the presence of fractures or tendon and ligament injuries. First of all, we need to take the ankle braking, and improve the X-ray, CT or nuclear magnetic examination to clarify the type of injury. If there is a fracture, tendon or ligament rupture, surgical fixation, tendon repair or reconstruction is necessary. All of the above medications should be used under the guidance of a doctor, avoiding self-medication.