Getting up in the morning and spitting in the mouth with blood may be chronic periodontitis, pharyngitis or nasal bleeding, specifically need to check the source of the blood, find the problem in time to deal with. 1. Chronic periodontitis: blood in the mouth in the morning may be caused by chronic periodontitis, long-term chronic periodontal inflammation, gums are red and swollen and easy to bleed, and blood can be found in the mouth in the morning. 2. Pharyngitis: smoking or local inflammation can cause pharyngitis, inflammation is heavy, capillary congestion rupture bleeding, can lead to blood in the sputum. 3. Nasal bleeding: when the nasal mucosa is dry or rhinitis, it may also bleed when sleeping and reach the mouth through the nasopharyngeal area, and blood in the mouth can be found in the morning. Morning spit in the mouth with blood, may also be caused by digestive system diseases (such as blood diseases), specific need to go to the hospital to check the cause of the disease, found that the problem is dealt with in a timely manner.