Severe acid reflux after total gastrectomy can usually be relieved by adjusting daily diet and medication. 1. Adjustment of daily diet: When acid reflux is severe, patients should pay attention to the daily diet to eat small meals, avoid overfilling, avoid spicy and stimulating food, and minimize the consumption of oranges, hawthorn, lemons and other acidic fruits. 2. Medications: After total gastrectomy, patients with severe acid reflux usually need to take acid-suppressing medications such as omeprazole enteric-coated capsules, rabeprazole sodium enteric-coated capsules, etc., which can reduce the secretion of gastric acid and improve the acid reflux; they can also take gastrointestinal stimulants, such as domperidone tablets, mosapride tablets, etc., which can promote gastric emptying and reduce the gastric reflux of acid to alleviate the symptoms of acid reflux. The above medications are recommended to be used under the guidance of a doctor. If the acid reflux is serious after total gastrectomy, it is recommended to seek medical treatment in time and standardize the treatment under the doctor’s guidance to avoid delaying the condition.