Digoxin belongs to the digitalis group of positive inotropic drugs with positive inotropic effects and is often used clinically to treat chronic heart failure. Since the difference between the therapeutic dose of digoxin and the toxic dose is not large, digoxin toxicity is easily caused if digoxin is overused. Once digoxin poisoning occurs, the patient’s heart failure will be aggravated, and there will be various types of arrhythmia, the common ventricular premature dystonic rhythm, non-paroxysmal junctional tachycardia, as well as atrial premature, atrial fibrillation, atrioventricular block, etc., tachyarrhythmia with conduction block is the characteristic manifestation of digoxin poisoning. In addition, patients with digoxin poisoning may also have gastrointestinal symptoms such as nausea, vomiting and poor appetite, as well as neurological symptoms such as blurred vision and yellow-green vision. Once digoxin poisoning occurs, it should be treated as soon as possible, and the usual use of digoxin must pay attention to the dosage of digoxin.