Newborns have not been sleeping may be some kind of physiological phenomenon, but also may be the symptomatic manifestation of certain diseases, such as vitamin D deficiency, gastrointestinal diseases and other factors related. 1. Physiological factors: (1) hunger: newborns usually start to sleep after eating enough milk, if they have not been sleeping, they may not have eaten enough, or fall asleep soon after being woken up by hunger, in a state of starvation leading to failure to sleep normally. (2) Environmental factors: for example, the environment is noisy, or the light in the bedroom is too bright, resulting in the newborn’s mental excitement can not sleep; or the indoor temperature is too high, the newborn wears too many clothes or quilt is too thick, resulting in the newborn’s body is hot and can not sleep. 2. Pathological factors: (1) lack of vitamin D: lack of vitamin D in the body can easily lead to increased excitability of the nervous system of newborns, symptoms of reduced sleep, difficulty in falling asleep, but also can be accompanied by crying at night, night terrors and other phenomena. (2) gastrointestinal diseases: newborns have physical discomfort, such as abdominal distention, abdominal pain, diarrhea and other gastrointestinal symptoms, can also lead to have not slept, mostly accompanied by lower limb flexion, crying phenomenon. Newborns have not been sleeping, there may be other reasons, it is recommended to go to the hospital in a timely manner, improve the examination to determine the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.