As with other tumors, its pathogenesis is multifaceted and is currently considered to be mainly due to the following: 1. Chemical factors: air pollution, water pollution, food pollution, indoor decoration pollution, etc. Meanwhile, people who are often exposed to chemical substances are also prone to develop the disease, especially those who are exposed to substances containing benzene. 2. Physical factors: radiation that can be seen everywhere in daily life, such as computers, cell phones, TV sets, microwave ovens, induction cookers, etc. It is clinically found that there are some low age tumor patients who have long time intensive internet experience. 3, viruses, bacteria and other infections: currently known are EBV, HIV, Helicobacter pylori, etc.. After some people are infected with viruses, genetic mutations occur in their cells, leading to the development of lymphoma, for example, people infected with HIV have a high chance of getting lymphoma. 4.Psychological pressure: Today’s society is becoming more and more competitive, learning, working, dealing with interpersonal relationships and other aspects of things to deal with, so people are generally under a lot of pressure, and long-term will inevitably cause a psychological tension and anxiety. If this state cannot be well relieved, the immune function of the body will decline and lymphoma will easily occur. 5.Imbalanced diet: Nowadays, many people have insufficient intake of trace elements such as zinc and vitamins, plus they eat a lot of white rice and white flour and meat for a long time, and stay away from coarse grains, vegetables and fruits, which leads to unbalanced nutritional intake and low immunity, which is also one of the causes of cancer. 6. Family aggregation: We sometimes see this phenomenon that several relatives in a family have tumors, some are the same tumor, some are different tumors, but this also shows that there is indeed family aggregation of tumors. This may be related to the similarity of genetic factors, living habits, lifestyles and living environment. Therefore, children of tumor patients should also be vigilant and have regular medical checkups.