The process of iodine-131 treatment includes the following three steps: 1. Before the formal iodine treatment, a thyroid examination, such as thyroid ultrasound, should be done to assess the size of the thyroid gland, which will help to formulate the specific iodine 131 dose, and to exclude any malignant tumor of the thyroid gland. 2. The iodine dose should be formulated according to the size of the thyroid gland, iodine absorption rate and other indicators, and should be taken at the relevant window of the hospital. 3. After taking the medication, one should rest in time and try not to eat within two hours of taking the medication, while one should pay strict attention to observe whether there are any adverse reactions in the organism to protect one’s life. The process can be performed to increase the efficacy of the drug.