Thigh burning pain may be caused by trauma, multiple peripheral neuritis, exposure to chemicals and other factors. 1. Trauma: if the leg movement is excessive, it may trigger muscle swelling and damage; or the thigh is squeezed, collision and other external injuries, which may cause localized damage, thus triggering localized fiery pain. 2. Multiple peripheral neuritis: clinical manifestations of the affected limbs feel abnormal, such as pins and needles, burning sensation and tenderness and other symptoms. 3. Contact with chemical substances: local contact with acid preparations if the acid chemical irritants, can also trigger thigh burning pain. The causes of thigh pain are many, it is recommended that patients seek medical examination to clarify the cause, and follow the doctor’s instructions for treatment.