Bone cement surgery has the risks of bone cement leakage, peripheral tissue damage and toxic reaction, but the general surgical risk is not high and it is a routine surgery. 1. Bone cement leakage: As bone cement becomes paste after dissolving, after injecting into human bone, if there is a defect or fracture at the back of vertebrae, the bone cement will leak out along the crack, especially when there is a defect at the back of vertebrae, it may lead to leakage of bone cement into the vertebral canal, which will compress the spinal cord and nerve roots, and in serious cases, it may lead to paralysis of human body. 2. Peripheral tissue damage: As the bone cement enters the human bone through puncture, it may damage the nerves, blood vessels and other tissues in the process of puncture. 3. Toxic reaction: most of the current bone cements are polymethylmethacrylate, which releases chemicals and generates heat during solidification in the body. These chemicals can lead to a sudden drop in the patient’s blood pressure, and if the blood pressure is too low, cardiovascular and cerebrovascular accidents may occur. There may be other risks associated with bone cement surgery, and patients are advised to go to a regular hospital to avoid adverse consequences.