There is no fixed time for metronidazole resistance to develop, and it varies with each person’s physical condition, the dosage of the drug used, and the type of pathogen. The degree of resistance to oral metronidazole varies with each person’s physical condition, and some people may be susceptible to induced metronidazole resistance. In addition, if the use of metronidazole dose is too large or insufficient, at the same time not in accordance with the norms, not in accordance with the instructions for the use of the words, and some of the course of use is not standardized, so it is also easy to induce the production of pressure resistance. Some pathogens are prone to produce metronidazole resistance, such as vaginal infection pathogens such as trichomonas. So you should use metronidazole regularly under the guidance of a specialist to avoid inducing resistance.