A high total bilirubin of 150μmol/L may be physiologic (strenuous exercise, etc.), liver disease (e.g., drug-induced hepatitis, viral hepatitis, acute jaundice hepatitis, cirrhosis, etc.}, or biliary tract obstruction (e.g., gallstones, cholecystitis, etc.). 1. Physiological high: for example, after doing strenuous exercise, the test will show a transient high total bilirubin, 2. Liver diseases: for example, drug hepatitis, viral hepatitis, acute jaundice hepatitis, cirrhosis, etc., which lead to damage of liver cells and decrease in the ability of liver to transfer bilirubin, resulting in high total bilirubin. 3. Biliary tract obstruction: for example, cholecystitis, gallstones, etc., due to the thickening of the gallbladder wall, narrow gallstones embedded in the gallbladder cavity causing obstruction, forming obstructive jaundice, resulting in elevated total bilirubin. There may be other reasons, it is recommended that patients consult a physician as soon as possible to standardize treatment.