Headache in the car is mainly seen in vestibular migraine, may also be caused by cerebral hypoxia, anemia, hypertension and neurosis, according to the patient’s physical condition to determine the cause of the disease.1, vestibular migraine: patients with a history of migraine headache will appear nausea, vomiting, photophobia, photophobia and aura, followed by paroxysmal vertigo. Often occurs when sitting in the car, if there is shaking will make the vestibular sensitivity, easy to cause the inner ear lymphatic fluid shock, leading to vestibular dysfunction, after nerve conduction, can cause vestibular migraine; 2, cerebral hypoxia: when the oxygen supply can not meet the metabolic needs of the brain tissues, there will be varying degrees of cerebral dysfunction. If the cerebral vascular contraction pulls the nerves, headache symptoms will appear. At the same time, prolonged hypoxia will damage the brain nerve cells leading to edema, causing increased intracranial pressure, pulling the meningeal nerves, headache, accompanied by nausea, vomiting and so on; 3, anemia: anemia patients due to a decrease in the oxygen-carrying capacity of the blood, the brain’s blood supply is insufficient to supply oxygen, in the car there will be a headache when the symptoms; 4, high blood pressure: the car ride due to the bumps in the road will lead to increased blood pressure, high blood pressure may have cerebral vasospasm symptoms, can lead to cerebral tissue ischemia. Symptoms, can lead to cerebral tissue ischemia, the occurrence of obvious headache, accompanied by dizziness, chest tightness, shortness of breath and other symptoms, the need to take antihypertensive drugs in a timely manner to treat; 5, neurosis: due to the car ride nervousness, fatigue, etc., can be caused by a decline in mental activity, dizziness, headache, anxiety, depression, fear and other symptoms, need to appropriate relaxation, can be taken orally to anti-anxiety drug treatment.