When is the best time to plug snow nordle is no clear rules, can be based on the patient’s own situation to decide, if there is any discomfort, can promptly to the obstetrics and gynecology consultation. Usually, the main component of chenoprogesterone is progesterone, also called progesterone vaginal delayed-release gel, mainly used in assisted reproductive technology in the supplemental treatment of progesterone. Generally only need to be given once a day, as to when the best time to give the drug, of course, is the most convenient time, generally at home before bedtime to give the drug is more convenient, but also easy to operate, other times because of less convenient, and other times to give the drug and bedtime to give no significant difference, so there is no clear requirement to say what time to give the drug, as long as the doctor’s request, according to the requirements of the prescription every day to give the drug on time If you can adhere to a certain duration of administration, for example, some prolonged dosing, which needs to reach 10-12 weeks, as long as you can adhere to the daily dosing schedule, do not fall behind, do not miss the dose, miss the dosing can be. In addition, we need to pay attention to two points, the first is to take a detailed look at the instructions before giving the drug, especially the method of administration, what position to use to give the drug, how to operate, and then what adverse reactions after the operation. The second is to pay attention to any discomfort during the use of the drug, to go to the hospital obstetrics and gynecology department in a timely manner to receive standardized treatment or consult a doctor, so as to make appropriate adjustments to the medication for individual circumstances. In daily life, if breakthrough bleeding or irregular vaginal bleeding occurs, non-functional causes should be considered. Also, if unexplained vaginal bleeding occurs, it should be diagnosed and treated promptly. In addition to this, since certolone treatment may cause some degree of fluid retention, the resulting diseases and symptoms, such as epilepsy, migraine, asthma, cardiac or renal insufficiency, should be closely monitored.