The chemical name of alcohol is ethanol. Acute ethanol poisoning, also known as acute alcohol poisoning, can occur after drinking a large amount of alcohol at one time. If the drinker appears to be euphoric, talkative, conceited, irritable, flushed or pale, dizziness, fatigue and other manifestations, usually no special treatment is needed, only need to bed rest, pay attention to keep warm. Excitement and restlessness may be appropriately restrained. If the drinker shows uncoordinated movements, incoherent speech, slurred speech, unsteady gait, blurred vision, nausea and vomiting, he or she should rest and avoid activities to avoid trauma. If the drinker is unconscious, slow breathing with snoring, incontinence, pallor, cold skin, purple lips and other manifestations, immediately send to the hospital or call 120 emergency, if possible, first given oxygen. When vomiting, make them lie on their side and remove the vomitus from their mouth and nose to prevent inhalation and asphyxiation. If respiratory arrest is detected, cardiopulmonary resuscitation (CPR) should be performed immediately until resuscitation is successful or 120 emergency personnel arrive. In comatose patients, pay attention to whether other drugs are taken at the same time. Focus on maintaining life function: ① maintain an open airway, adequate oxygen supply, artificial respiration, tracheal intubation if necessary. ② Maintain circulatory function, pay attention to blood pressure, pulse, intravenous input of 5% glucose saline solution. ③ ECG monitor arrhythmia and myocardial damage. ④ Keep warm and maintain normal body temperature. ⑤ Maintain water, electrolyte, acid-base balance, and supplement magnesium when blood magnesium is low. In addition, intramuscular injection of vitamin B1, 100mg. naloxone can help to shorten the time of coma, 0.4mg slow intravenous injection, if necessary, can be repeated once.