The change of Hepatitis B virus load from Triple III to Minor II means that the viral load has decreased, the transmission rate has decreased, the disease has improved, and the need for treatment needs to be decided according to the liver function tests. 1. Normal liver function: It is recommended that patients need to undergo further Hepatitis B virus DNA testing, if the Hepatitis B virus DNA load also decreases. At this time, if the patient receives liver ultrasound examination, which shows that liver function is normal, antiviral treatment is not needed. 2. Abnormal liver function: If the patient undergoes liver ultrasound examination, and the liver function is abnormal, and the transaminases and bilirubin are elevated, the patient needs to receive antiviral treatment, and the first-line antiviral drugs used in the treatment of hepatitis B virus include entecavir dispersible tablets and tenofovir disoproxil fumarate tablets, etc. The patient may need to receive antiviral treatment if the liver function is abnormal. Abnormal liver function has a significant impact on the patient’s body, so the patient needs to actively seek treatment under the guidance of a specialist.