Multiple small lymph nodes in the root of the mesentery may be mesenteric lymph node inflammation, mesenteric tumor and other diseases. 1. Inflammation of mesenteric lymph nodes: Inflammation of lymph nodes at the root of the mesentery is caused by inflammation of the intestine due to bacterial infection, which will result in abdominal pain, nausea, vomiting and other symptoms, and can be treated with oral cefixime, amoxicillin and other medicines under the guidance of a doctor. 2. Mesenteric tumor: mesentery is the part that connects the intestines to the abdominal cavity, tumors on the mesentery are called mesenteric tumors, which will have symptoms such as multiple small lymph nodes at the root of mesentery, abdominal mass, and so on, and the tumors can be removed through surgical treatment. Therefore, patients with multiple small lymph nodes in the mesenteric root should go to the hospital as soon as possible to clarify the cause of the disease, and carry out symptomatic treatment after diagnosis to avoid delaying the condition. Normally, they should have a light diet and avoid eating cold and spicy food.