When the anal opening is sweaty and moist, it may be related to fecal residue, anal fissure and other factors, generally can be treated by regular cleaning or use of drugs. 1. Fecal residue: when you don’t pay attention to personal hygiene in daily life, it may cause fecal residue, which may lead to the phenomenon of moist anus, and the symptom can be relieved by regular cleaning, and it is suggested that you should choose the underpants with better breathability in daily life. 2. Anal fissure: usually due to defecation too hard, fecal dryness and other factors lead to the formation of ulcerative fissures in the perianal skin, if not treated in time, may lead to inflammation stimulation, so that the secretion out, thus appearing in the anal opening sweating wet phenomenon. Patients can use hemorrhoidal suppositories, hemorrhoidal quick Ning tablets and other drugs for treatment. Sweating and dampness at the anal opening may also be related to hemorrhoids and other diseases, and it is recommended that patients seek medical examination in time to avoid delaying the condition. Drugs should be applied under the guidance of a doctor.