The normal range of estradiol in early pregnancy is approximately 100-300 ng/L. This test has a wide range of values and increases relatively quickly in the early stages of pregnancy. If there is a significant decrease, the patient cannot exclude the possibility of pre-eclampsia, miscarriage, or cessation of embryonic growth and development. It is recommended that pregnant women should have regular tests of chorionic gonadotropin, blood progesterone and estradiol during pregnancy, so that the growth and development of the embryo can be clearly understood according to the results of these tests and the condition can be detected and treated in time. It is necessary to pay attention to the combination of rest and exercise, avoid excessive fatigue, and avoid excessive emotional tension and anxiety, which is conducive to a smooth pregnancy.