There is no absolute answer to the question of which is the best cure for acute and chronic leukemia. Both acute and chronic leukemia have specific types, and different types have different treatment plans and degrees of difficulty. At present, the treatment of chronic leukemia is more mature, and after regular active treatment, the prognosis is relatively good. 1. Acute leukemia: usually divided into acute lymphoblastic leukemia and acute granulocytic leukemia, and acute granulocytic leukemia can be divided into 8 types, with different treatment modalities and different degrees of difficulty. At present, combined chemotherapy (cytarabine), immunotherapy (carT cells), targeted drug therapy (cidapenem, vinblastine) and hematopoietic stem cell transplantation are mostly used. 2. Chronic leukemia: it can be divided into chronic lymphocytic leukemia and chronic granulocytic leukemia. At present, the targeted drug therapy for chronic granulocytic leukemia has been more mature, including imatinib, etc., but hematopoietic stem cell transplantation is still an important method for cure. Chronic lymphocytic leukemia treatment drugs include nitrogen mustard phenylbutyrate, ibrutinib, etc., and patients are expected to have long-term survival. Therefore, it is impossible to give a general answer to which is better to cure acute and chronic leukemia, only for the time being, it is possible that chronic leukemia has a better prognosis after regular treatment. The specific use of drugs should be under the guidance of physicians.