The hepatitis B virus quantitative nucleic acid test, often referred to as the hepatitis B DNA test, generally costs about 100 yuan, and the lower limit of the test reference value is 500 IU/ml. If the hepatitis B virus test is highly sensitive, the cost is higher, generally around 600 yuan, which may vary from place to place and from hospital to hospital. For high sensitivity hepatitis B virus test, the test results are more accurate and can determine the efficacy of antiviral treatment. For hepatitis B patients, especially those with cirrhosis, if the routine hepatitis B DNA test is negative and less than 500 IU/ml, it is recommended to do high sensitivity hepatitis B virus test.