Patient: Description of the condition (onset, main symptoms, hospital visited, etc.): A lump was found in the right breast in 2009, and the surgery revealed that it was invasive ductal carcinoma, breast-conserving surgery was performed, pathology results P53(+) ER(-) PR(-) CerbB-2(++) PS2(-), in 2011 there was an enlarged lymph node on the left scapula, after cutting out, it was said to be breast cancer metastasis, pathology analysis ER ER positive 40%, staining intensity: weak, PR positive 35%, staining intensity: weak, Ki-67 positive 65%, CerbB-2(3+),CK5/6(-),EGFR(-) In the county hospital in 2009, the 1st to 4th cycle with FAC chemotherapy, followed by radiation therapy in January, and the 5th to 8th with paclitaxel. Now CT, ECT found bone metastasis and some tissue metastasis For our county level working class income level, how to treat this disease combined with Chinese and Western medicine medical oncology. 1. endocrine therapy with tamoxifen 10 mg twice daily. 2. If already treated with tamoxifen and the disease still progresses, then consider subcutaneous injection of goserelin once a month, then letrozole 2.5 mg once a day. 3. or removal of ovaries followed by letrozole 2.5 mg once daily. 4. Bonine 60 mg once a month intravenous drip. 5. Herceptin may be considered.