The absence of thyroid gland in women may affect fertility. The thyroid gland is an endocrine organ that secretes thyroxine and triiodothyronine, which not only participates in the metabolism of various substances in the body, but also has an important influence on the development and maturation of the gonads and the maintenance of normal menstruation and reproductive function. Hypothyroidism that occurs before puberty may result in impaired sexual development and delayed puberty. During the reproductive years, menstrual disorders occur, with clinical manifestations of scanty and sparse menstruation, or even amenorrhea. It is recommended that female patients without thyroid gland should go to Obstetrics and Gynecology Department or Endocrinology Department of regular hospitals in time to improve the relevant examinations and have children under the guidance of the doctor, so as to avoid delaying the condition or leading to adverse consequences.