The common damage caused by chemotherapy includes bone marrow suppression, gastrointestinal reaction, abnormal liver and kidney function, local irritation, and affecting fertility. All chemotherapeutic drugs kill tumor cells and at the same time harm normal cells to varying degrees, resulting in bone marrow suppression, gastrointestinal reactions, liver and kidney dysfunction, local irritation, and reproductive effects. Bone marrow suppression includes reduction of white blood cells and platelets, anemia and so on. Gastrointestinal reactions include nausea, vomiting, decreased appetite, and diarrhea. Local irritation, such as phlebitis, local tissue necrosis caused by extravasation of chemotherapeutic drugs. Abnormal liver function and renal function indicators, etc. It also affects the reproductive function, such as testicular atrophy, reduced sperm count and quality in men, and impaired ovarian function in women. In conclusion, chemotherapy harms the body in many ways, and the size of the harm is related to the chemotherapy program, the patient’s condition, and so on, and varies from person to person. It is recommended that patients go to regular hospitals for diagnosis and treatment, follow the doctor’s instructions to cooperate with the treatment, and deal with any discomfort in time.