The treatment principles of bipolar disorder have four specific points as follows: 1. Early identification and early treatment of bipolar disorder, sufficient amount, sufficient course and whole course of treatment; 2. Adopting comprehensive treatment, including medication, physical therapy and psychosocial intervention therapy; 3. Establishing the concept of long-term treatment, bipolar disorder is easy to relapse, emphasizing patient compliance and long-term treatment; 4. Needing the support and cooperation of family members and people around, and Supervise the patient to take medication and review regularly. During the use of mood stabilizer drugs, regular monitoring is required, including blood biochemical examination and drug blood concentration monitoring. The preferred mood stabilizers for manic states can be combined with antipsychotics and benzodiazepines. Commonly used mind-stabilizing drugs include lithium carbonate, sodium valproate, lamotrigine, and phenytoin sodium drugs. Antipsychotics are now dominated by atypical antipsychotics, including olanzapine, quetiapine fumarate, and aripiprazole. Sedative-hypnotic drugs are dominated by benzodiazepines, such as alprazolam and clonazepam. When using drugs, patients must use them under the guidance of doctors, and must not use them on their own. Mania treatment is divided into three phases, as follows: 1, the acute treatment period, which requires at least 4-6 weeks; 2, the consolidation period, the application of the acute treatment drug dose does not reduce the need for at least 2-3 months; 3, the maintenance period, there is no special limit, according to the patient’s condition to do maintenance treatment, now the international, including the domestic has not been very accurate time, probably at least 1 year, the doctor needs to be based on the patient It takes at least 1 year, and the doctor needs to decide according to the patient’s condition.