Metronidazole and Cephalosporin can generally be taken together, but should be taken under medical supervision. Metronidazole belongs to the class of anti-anaerobic drugs, while Cephalosporin has antibacterial activity against gram-negative and gram-positive bacteria. The antimicrobial spectrum of the two types of drugs is different, if the patient has inflammatory infections, bacterial infections, anaerobic infections, etc., such as dental inflammation, inflammation in the mouth, or deep wound infections, etc., the simultaneous administration of metronidazole and cephalosporin can kill bacteria as well as anti-anaerobic bacteria. So metronidazole and cephalosporin can be taken together. Metronidazole mainly through the inhibition of bacterial deoxyribonucleic acid synthesis, so as to achieve antibacterial effect, clinically used in the treatment of amebiasis, Trichomonas vaginalis, anaerobic bacteria caused by infections, etc., during the use of medication, there are occasionally nausea, vomiting, skin rashes and other adverse reactions, pregnant women and breastfeeding women are prohibited. Cephalosporin inhibits the synthesis of cell wall to achieve antibacterial effect, mainly used for the treatment of staphylococcus, streptococcus and other bacterial infections caused by tonsillitis, acute bronchitis, pneumonia, etc., and its common adverse reactions include diarrhea, abdominal pain, gastric discomfort, and so on, cephalosporin allergy is prohibited. Alcohol and beverages containing alcohol are prohibited while taking metronidazole and cephalosporins. If you need to take metronidazole and cephalosporins, you should use them under the guidance of a physician, and should not use them on your own to avoid adverse reactions.