Hidden pain on the chest and discomfort down the throat to the chest may be caused by problems such as reflux esophagitis and esophageal cancer. 1. Reflux esophagitis: generally refers to heartburn, acid reflux and difficulty in swallowing caused by excessive gastric and duodenal contents refluxing into the esophagus, manifesting as reflux, heartburn, chest pain, difficulty in swallowing and other symptoms, which can be treated with medicines such as omeprazole, moxapride and magnesium alumina carbonate according to doctors’ instructions. 2. Esophageal cancer: generally refers to cancer of epithelial origin in the esophagus between hypopharynx and esophagogastric union, manifesting symptoms such as choking sensation after eating, retrosternal pain, progressive dysphagia, back pain, etc. It can be treated with drugs such as fluorouracil, cisplatin, doxorubicin, oxaliplatin, epimedicine, paclitaxel and so on according to medical advice. Hidden pain on the chest and throat down to the chest discomfort need to go to the hospital in time to confirm the diagnosis, under the guidance of the doctor’s instructions for standardized treatment.