Potassium permanganate is a topical medication, the duration of which depends on the degree of symptomatic relief, and is used for the treatment of localized skin infections usually requiring 3 to 7 days or as directed by a physician. Potassium permanganate is used as an adjunctive treatment for infectious inflammation of the skin surface, eczema, and localized ulcers. The drug is a topical drug and there is no absolute standard for its duration of use. For disinfection of localized skin ulcers, without specific medical advice, wet compresses may be applied temporarily for 3 to 7 days, and the drug may be discontinued after assessing the improvement of the condition. It should be noted that potassium permanganate needs to be diluted in the prescribed proportion and the temperature of the solution adjusted appropriately before use. High concentration of the drug may lead to local chemical damage. If local tingling, redness or swelling occurs after administration of the drug, stop using the drug immediately and rinse with water. The drug is forbidden to be taken orally, and its use needs to be under the guidance of a clinician.